NAD+: A Promising Tool for Energy and Nerve Function in AMN

NAD+ (nicotinamide adenine dinucleotide) is a critical coenzyme found in every cell of the body, playing a vital role in energy production, DNA repair, and mitochondrial function. For individuals with Adrenomyeloneuropathy (AMN)—a rare genetic disorder that affects the spinal cord and nervous system ,NAD+ can be particularly beneficial due to its ability to support cellular energy and combat oxidative stress.

In AMN, mitochondrial dysfunction and inflammation contribute to the gradual loss of nerve function. Boosting NAD+ levels helps enhance mitochondrial efficiency, promoting better energy production in nerve cells and reducing cellular damage. NAD+ also activates sirtuins, proteins that regulate inflammation and repair damaged DNA, which may slow the progression of neurological decline.

Additionally, NAD+ supports healthy myelin maintenance, the protective coating around nerves that deteriorates in AMN, helping to preserve nerve communication and mobility. While NAD+ is not a cure, maintaining optimal levels through precursors like NMN or NR, lifestyle changes, or supplementation may improve energy, focus, and overall neurological health.

For those living with AMN, NAD+ represents a promising tool in supporting mitochondrial resilience and improving quality of life through enhanced cellular repair and reduced inflammation.